Acrab

常見例句

• No deletion or point mutation in acrAB gene were found in Mar and susceptible clinical Escherichia coli isolates.
  多重耐藥株以及敏感株acrAB基因擴增產物無點突變和缺失。
• Chromosomally mediated multidrug resistance in Salmonella typhimurium is generally attributed to the overexpression of the acrAB locus and the mutation in topoisomerase genes.
  AcrAB外流泵系統(tǒng)的過度表達和拓撲異構酶基因突變是導致鼠傷寒沙門菌產生多重耐藥性 (MAR)的重要原因。
• Methods Accumulation of ciprofloxacin in clinical isolates of Escherichia coli was measured by fluorometry, and acrAB gene was identified by PCR and Southern blot.
  方法 應用熒光法測定臨床分離大腸桿菌對環(huán)丙沙星的主動外排功能 ; PCR及Southernblot測定主動外排系統(tǒng)AcrAB結構基因acrAB ;
• There was high degree of homology in nucleotide sequence between the PCR expandedATCC 10031 acrAB gene sections and the corresponding ones in Escherichia coli.
  PCR擴增的 ATCC 10031的 acrAB基因片段同大腸埃希菌acrAB基因相應片段,在核苷 序列上具有很高的同源性。
• The acrAB locus encode the efflux pump AcrAB,which confers multidrug tolerance,controlled by the regulon marRAB. Mutation in the gyrase and topoisomerase IV lead to fluoroquinolones resistance, mainly arise in gyrA and parC genes.
  AcrAB外流泵系統(tǒng)的合成有多重耐藥調節(jié)子 (marRAB)調控 ,AcrAB與多種抗生素的耐藥有關。 拓撲異構酶 (topoisomerase)的突變主要與氟喹諾酮類藥物的耐藥性有關 ,突變主要發(fā)生在gyrA ,parC基因上
• It suggested that the level of resistance of isolates would be related to selecting pressure of fluoroquinolones and induced gene mutations of DNase and topoisomerase IV could not activate AcrAB efflux pump system.
  提示臨床分離的雞大腸桿菌O 78的耐藥水平與喹諾酮類藥物的選擇性壓力有關,它誘導了DNA旋轉酶和拓撲異構酶IV的基因突變,可能不能激活A crAB外輸泵。
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